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. 2010 Aug 31;2010:268589. doi: 10.1155/2010/268589

Figure 4.

Figure 4

T-helper cell differentiation. Naïve Thp cells are able to differentiate into functional effector cell subsets according to the cytokine milieu. The differentiation process is initiated by antigen encounter. Naturally occurring regulatory T-cells are produced in the thymus. The different roles of the effector cells in the periphery are indicated in the figure.