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B-1a lymphoproliferations from SXR−/− animals are transplantable. A, B-1a cells are found in spleen of NOD/SCID recipient animals 2 wk after transplant. Peripheral blood shows no B-1a cells. B, B-1a cells are found in spleen, lymph nodes, unchallenged peritoneal lavage, and blood 6 wk after transplant as measured by flow cytometry. C, Spleen weight (milligrams) of NOD/SCID recipient animals 2 and 6 wk after transplant.
