Table 2.
Organ and body weights in E18.5 female Cited1 heterozygotes with placental insufficiency
| Genotype | Body weight (g) | Brain weight (mg) | Liver weight (mg) | Lung weight (mg) | Kidney weight (mg) |
|---|---|---|---|---|---|
| Cited1M+/− | 1.2 ± 0.09 | 73.1 ± 7.1 | 63.9 ± 9.3 | 36.6 ± 6.3 | 11.3 ± 2.2 |
| Cited1P+/− | 1.0 ± 0.11a | 68.2 ± 7.6 | 47.3 ± 10.7a | 26.7 ± 5.6a | 9.1 ± 1.8a |
Numbers of embryos examined were as follows: Cited1M+/− (without placental insufficiency), n = 30 for body and brain weights, and n = 20 for other organs weights; Cited1P+/− (with placental insufficiency), n = 20 for body and brain weights, and n = 12 for other organ weights. Results are expressed as means ± sd organ or body weight in grams or milligrams, as indicated.
Student's t test: P < 0.01 vs. Cited1M+/− embryos.