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. Author manuscript; available in PMC: 2012 May 1.
Published in final edited form as: J Immunol. 2011 Mar 23;186(9):5489–5496. doi: 10.4049/jimmunol.1001623

Figure 5.

Figure 5

TRAF6 peptide activates human platelets in the absence of CD14. Platelets were treated with a chimeric Traf6-antennapedia peptide (5 μM) and lysates were made at stated times. (A) The Traf6 chimeric peptide caused a significant increase in spliced IL-1β mRNA. JNK (B) and Akt (C, D) phosphorylation measured by ELISA. Data is expressed as the ratio of phospho-kinase to total kinase. Error bars = +/− 1 SE, N=7 for Fig. 5A and N=3 for 5B–5E.