Skip to main content
. Author manuscript; available in PMC: 2012 May 1.
Published in final edited form as: Mol Cell Neurosci. 2011 Mar 17;47(1):61–70. doi: 10.1016/j.mcn.2011.03.003

Figure 1. Schematic representation of the experimental paradigm.

Figure 1

GFP+ bone marrow-derived cells (BMDCs), enriched for the hematopoietic stem cell (HSC) population (Sca-1+, c-Kit+, Lin−), are isolated from male GFP transgenic mice through FACS. BMDCs/HSCs are next infected with one of the scAAV7 vectors at 1 × 105 viral particles/cell and transplanted into irradiated female Sca1154Q/2Q recipients through retro-orbital sinus injections.