Figure 1.

Neuronal densities in hippocampal fields involved in the neuropathology of hippocampal sclerosis. A, CA1. B, CA4 (corresponding to CA3c in the rodent). C, GCL of the dentate gyrus. Neuronal counts and analyses were performed as described in Materials and Methods. As evident from the figure, whereas specimens from epileptic individuals without hippocampal sclerosis (NHS) had neuronal densities comparable with those of autopsy specimens (AUT), significant reductions were noted in the HS tissue. Values are means ± SEM from 10 AUT, 10 NHS, and 17 HS hippocampi. CA, Cornu ammonis. Asterisks indicate statistical significance.