Table 2.
Frequencies of occurrence of the mucin type and non-mucin-type O-glycosylations at residue sites in ID regions. The total numbers of Ser and Thr residues are also shown for reference. 190 proteins were taken from UniProt 14.0, and ID regions were obtained from DICHOT [40,41].
| O-linked type | Number of proteins | Number of sites in ID | Total number of sites in the proteins | Ratio to be in ID (%) | |||
|---|---|---|---|---|---|---|---|
| O-linked | Ser/Thr | O-linked | Ser/Thr | O-linked | Ser/Thr | ||
| O-GalNAc | 107 | 399 | 2,779 | 465 | 7,228 | 85.8 | 38.4 |
| O-GlcNAc | 28 | 45 | 4,076 | 57 | 5,287 | 78.9 | 77.1 |
| O-Gal | 14 | 23 | 376 | 43 | 1,365 | 53.5 | 27.5 |
| O-Xyl | 20 | 34 | 649 | 40 | 1,593 | 85.0 | 40.7 |
| O-Fuc | 8 | 1 | 62 | 14 | 572 | 7.1 | 10.8 |
| O-Glc | 8 | 0 | 91 | 8 | 447 | 0 | 20.4 |
| O-HexNAc* | 4 | 3 | 94 | 4 | 136 | 75.0 | 69.1 |
| O-Hex** | 1 | 1 | 23 | 1 | 53 | 100.0 | 43.4 |
*
O-HexNAc (O-GalNAc or O-GlcNAc)
**
O-Hex (O-Gal or O-Glc)