Figure 6.

Mild reduction in the number of TrkB-expressing cells in Avil^Cre/+; Shox2^flox/flox mice. A, In situ hybridization confirms the loss of Shox2 expression in the DRGs from Avil^Cre/+; Shox2^flox/flox mice. B, Representative images of TrkB expression in control and Avil^Cre/+; Shox2^flox/flox mice at E18.5 and P2. C–F, Quantification of the numbers of TrkB- (C), TrkC- (D), Ret- (E), and TrkA-expressing (F) DRG neurons per unit area in control and Avil^Cre/+; Shox2^flox/flox mice at E18.5 and P2. *p < 0.001. Error bars represent ±SEM. Scale bar, 100 μm.