Skip to main content
. 2011 May 3;108(20):8390–8395. doi: 10.1073/pnas.1101747108

Fig. 4.

Fig. 4.

Angiogenesis-related protein expression in CRIP2-expressing clones. (A) Results of the angiogenesis protein array of the vector-alone BSD-C5 and CRIP2-expressing clones. Duplicate spots: 1, angiogenin; 2, IL-6; 3, IL-8; 4, MCP1; 5, PDGF-BB; 6, RANTES; 7, VEGF; 8, uPAR. (B) Summary of the relative expression of angiogenesis-related proteins in the CRIP2-expressing clones. Relative expression was calculated by comparing the intensity on the protein array of CRIP2-expressing clones vs. the vector-alone. (C) VEGF ELISA of the vector-alone and CRIP2-expressing clones. The total VEGF protein concentration (pg/mL) in the conditioned media of the vector-alone and CRIP2-expressing clones (+dox) was determined. (D) qPCR analysis verifying mRNA transcription levels of candidate genes identified by angiogenesis protein array in the CRIP2-expressing clones. The fold changes were compared with those of the vector-alone BSD-C5. *P < 0.05 and **P < 0.05, statistically significant differences compared with the vector-alone control and corresponding +dox control, respectively.