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. 2011 Jun;337(3):876–886. doi: 10.1124/jpet.111.180224

Fig. 2.

Fig. 2.

Identification of the metabolites of PI by RLM. A, HPLC chromatogram of an extract of RLM incubated with PI for 30 min; PI and two of its metabolites are identified. PI and its metabolites were extracted and fractionated by HPLC as described under Materials and Methods. B, MS and MS/MS spectrum of hydroxyl-PI fraction collected from HPLC. C, MS and MS/MS spectrum of carboxyl-PI fraction collected from HPLC. D, metabolic transformations of PI by liver microsomes.