Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Correlation of PI metabolite levels with tumor volume. Mice with SW480 colon cancer xenografts were sacrificed 1 h after the last dosing, and ibuprofen levels in mouse blood and tumors were determined as described under Materials and Methods. A significant correlation (p = 0.016) between plasma levels of ibuprofen and tumor volume (top) and a trend between tumor levels of ibuprofen and tumor volume (bottom) were observed.
