Table 1.
Characteristics of HIV-1 Seropositive and Seronegative Youth Selected from the REACH Cohort
| Characteristics | HIV+youth | HIV−youth |
|---|---|---|
| No. of subjects | 60a | 20b |
| Sex ratio (M/F) | 0.33 (15/45) | 0.67 (8/12) |
| Ethnicity | ||
| African-American (AA) | 44 | 11 |
| Otherc | 16 | 9 |
| Age at visit 1d | 17.6 ± 1.3 | 17.6 ± 0.8 |
| Age at visit 2d | 18.4 ± 1.4 | 17.9 ± 1.0 |
| Interval (in days) between visits | 237 ± 107 | 170 ± 25 |
| BMI at visit 1 | 27.6 ± 7.3 | 28.3 ± 9.5 |
| BMI at visit 2 | 27.5 ± 7.5 | 28.4 ± 9.7 |
| Earliest visit date | March 1996 | March 1996 |
| Latest visit date | October 2000 | November 1999 |
| Plasma HIV-1 viral load (log10 copies/ml) | ||
| Visit 1 | 3.68 ± 1.57 | NA |
| Visit 2 | 3.69 ± 1.68 | NA |
| CD4+ T cell counts (cells per μl) | ||
| Visit 1 | 502 ± 342 | 1016 ± 345 |
| Visit 2 | 480 ± 378 | 870 ± 368 |
| Change (visit 2 to visit 1 ratio) | 0.93 ± 0.30 | 0.86 ± 0.24 |
a
Representative of HIV-1-seropositive youth in the REACH cohort (duration of infection unknown).
b
With an emphasis on relatively equal representation of African-Americans and others. NA, not applicable.
c
Mostly Hispanic Americans in this group.
d
These selected visits correspond to the first two eligible for analyses of HIV-1-related outcomes in the absence of antiretroviral therapy. Summary data as shown correspond to mean ± standard deviation.
HIV+, HIV-1 seropositive; HIV−, HIV-1 seronegative.