Table 2.
Pairwise Correlation among Three Plasma Analytes and Two HIV-1-Related Outcomes in 60 Youth from the REACH Cohorta
| Parameter | IL-10 | IL-18 | Soluble CD30 | HIV-1 viral load | CD4+T cell |
|---|---|---|---|---|---|
| IL-10 | 0.749 (<0.0001) | 0.353 (<0.01) | 0.397 (<0.01) | 0.434 (<0.001) | −0.407 (0.001) |
| IL-18 | 0.428 (<0.001) | 0.771 (<0.0001) | 0.259 (<0.05) | 0.402 (<0.01) | −0.449 (<0.001) |
| Soluble CD30 | 0.499 (<0.0001) | 0.334 (0.009) | 0.852 (<0.0001) | 0.523 (<0.0001) | −0.395 (<0.01) |
| HIV-1 viral load | 0.594 (<0.0001) | 0.404 (0.001) | 0.568 (<0.0001) | 0.869 (<0.0001) | −0.797 (<0.0001) |
| CD4+ T cell | −0.594 (<0.0001) | −0.430 (0.001) | −0.510 (<0.0001) | −0.823 (<0.0001) | 0.913 (<0.0001) |
a
Each individual is analyzed for two treatment-free visits within the first 3 years of longitudinal follow-up study. Results (Spearman ρ and p values in parentheses) from visit 1 are over the diagonal; results from visit 2 are below the diagonal; comparison between visit 1 and visit 2 are in italics. The best predictor of HIV-1 viral load within each visit is shown in bold.