Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2011 Feb 7;192(3):373–382. doi: 10.1083/jcb.201010021

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2011 Yu et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

PMC Copyright notice

Figure 2. — Illustration of current and potential applications of CTC technologies. The peripheral blood of a cancer patient is collected and processed through various CTC isolation technologies. CTCs are captured along with contaminating leukocytes. Immunostaining for specific markers and FISH for genomic amplification and translocation can be applied to CTCs. DNA or RNA can be extracted from the CTCs and subjected to sequencing, quantitative RT-PCR (qRT-PCR), and potential expression profile analysis. Viable cells can be released and propagated in cell culture.