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Characterization and Pharmacokinetic Data for the Evaluated Polymer-DOX Conjugates.
| Polymer-DOX conjugate | PEG monomer Mw (kDa) | Dox Loading (wt %) | Hydrodynamic diameter (nm) | t1/2,β (h)* |
|---|---|---|---|---|
| 1 | 1 | 6.6 | 8±2.3 | 28.6±2.7 |
| 2 | 1 | 8.4 | 35±6.4 | 31.2±3.4 |
| 3 | 1 | 10.2 | 41±7.5 | 31.7±4.2 |
| 4 | 2 | 8.4 | 56±10.8 | 25.7±5.3 |
Values are the mean ± S.D., n=3.
