Table 3. Pooled estimates of the percentage of manifestations among symptomatic NCC patients using random-effect binomial models.

Manifestation		Age group
	All	Children	Adults
Seizures/epilepsy	78.8% (65.1%; 89.7%)	78.9% (70.5%; 86.2%)	63.2% (51.9%; 73.8%)
Headaches	37.9% (23.3%; 53.7%)	27.7% (20.7%; 35.2%)	25.9% (10.7%; 45.0%)
Signs of Intracranial Pressure/Hydrocephalus/Papilledema	11.7% (6.0%; 18.9%)	22.7% (10.2%; 38.5%)	16.3% (5.3%; 31.8%)
Meningitis symptoms	7.9% (2.7%; 15.5%)	11.2% (5.2%; 19.0%)	5.6% (1.9%; 12.8%)*
Cranial nerve palsy	2.8% (0.1%; 14.5%)*	6.0% (0.6%; 16.2%)	NA
Gait abnormality/ataxia	6.0% (1.9%; 12.1%)	2.4% (0.2%; 7.2%)	5.6% (1.9%; 12.8%)*
Focal deficits	16.0% (9.7%; 23.6%)	12.5% (7.6%; 18.4%)	11.8% (4.1%; 22.9%)
Visual changes	5.6% (1.1%; 13.5%)	3.5% (1.3%; 6.7%)	NA
Altered mental state/psychiatric symptoms	4.5% (1.5%; 9.0%)	4.0% (0.5%; 13.4%)*	28.1% (0.5%; 74.9%)
Pyramidal signs	NA	11.6% (0.0%; 42.9%)	NA

*: One study with binomial 95%CI.

NA: No data Available.