Figure 4. Model-estimated combined impact of MDA and vector control and the potential for elimination.

(A) Vector control is scaled up in year 0, with or without 2 rounds of MDA during the first year. B), C) & D) Probabilities of local elimination in an isolated population of (B) 1000, (C) 10,000 or (D) 500,000 using vector control alone or in combination with MDA. Transmission is moderately seasonal and MDA is given prior to the transmission season.