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. 2011 May 24;6(5):e20143. doi: 10.1371/journal.pone.0020143

Table 1. Mean inhibitory concentrations (IC50) of OMP and 5-FU in various human pancreatic cancer cell lines.

cell line OMP PZL 5-FU Gemcitabine
IC conf. int. IC conf. int. IC conf. int. IC conf. int.
MiaPaCa-2 42.4 38–45 68.4 57.8–79.7 0.20 0.12–0.27 0.021 0.013–0.028
ASPC-1 11.2 7.1–15.4 38.2 12.3–64.1 0.45 0.35–0.55 0.036 0.007–0.07
Panc-1 31.8 13.4–49.0 22.2 10.7–33.8 0.57 0.38–0.76 0.24 n.n.-0.57
Colo357 26.4 20.0–32.8 69.7 46.6–92.8 0.48 0.36–0.60 0.0032 0.0008–0.007
PancTu-1 20.7 5.9–35.4 43.8 25.1–62.5 0.17 0.08–0.26 0.035 n.n.-0.09
Panc-89 9.1 8.4–9.7 98.8 89.2–108.4 0.20 0.08–0.26 0.005 0.0005–0.01

The IC50 were determined by ATP-bioluminescence. All values are listed in µg/ml.

Abbreviations: conf. int. - 90% confidence intervals.