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Predicted AUC24/MIC in children using reported vancomycin clearances from the literature. Values >400 noted in bold. MIC, μg/ml.
| Source | AUC24/MIC
|
|||||
|---|---|---|---|---|---|---|
| Dose 40 mg/kg/day | Dose 60 mg/kg/day | |||||
| MIC 0.5 | MIC 1.0 | MIC 2.0 | MIC 0.5 | MIC 1.0 | MIC 2.0 | |
| Schaad et al. | 515 | 258 | 129 | 773 | 386 | 193 |
|
| ||||||
| Wrisko et al. | 727 | 364 | 182 | 1091 | 545 | 273 |
|
| ||||||
| Lamarre et al. | 777 | 388 | 194 | 1165 | 583 | 291 |
|
| ||||||
| Chang | 702 | 351 | 175 | 1053 | 526 | 263 |
