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Coulter counter analysis of PEG4-acid (left) and PEG4-OH (right). No immune response was noted for the saline group or for the lowest percent exchange groups for either ligand. However, an immune response was noted for higher percent exchanges of PEG4-acid at 4 weeks where no immune response was noted for PEG4-OH. This suggests higher percentages of PEG4-OH may be exchanged than PEG4-acid without triggering an immune response.
