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. Author manuscript; available in PMC: 2012 May 10.
Published in final edited form as: J Control Release. 2011 Jan 22;151(3):256–262. doi: 10.1016/j.jconrel.2011.01.014

Figure 4. DNA distribution in the skin after i.d. DNA injection and non-invasive EP.

Figure 4

A, B, C, Skin observation by flurorescence stereoscope after delivery with Fluorescein-labeled plasmid. Pictures were taken at post-delivery 1 hour. One representative picture of 2 sites was shown here. Delivery group: A, control; B, 50µL-IO: 50µL DNA without EP; C, 50µL-1EP: 50µL DNA with 1 EP on the injection site. D, E, total 4 cryosections (2 sections per sample) of each delivery were analyzed. Cell nuclei were blue-stained by DAPI. Cy™3-labeled DNA was shown red as indicated by arrows. D, One representative section of 50µL-IO was presented. E, One representative section of 50µL-EP was presented (magnification = 100, scale bar=100µm).