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. Author manuscript; available in PMC: 2012 May 10.
Published in final edited form as: J Control Release. 2011 Jan 10;151(3):271–277. doi: 10.1016/j.jconrel.2011.01.004

Fig. 1.

Fig. 1

(A) Schematic illustration of two different types of PpIX/PEG-PLA micelles from non-covalent encapsulation and covalent conjugation methods. At low loading density (i.e. 0.2%), PpIX exists as monomers in both micelle formulations; at high loading density (i.e. 4%), PpIX is present as aggregates or dimers in encapsulated and conjugated micelles, respectively. (B) A representative transmission electron microscopy (TEM) image of 4% PpIX-conjugated micelles counter-stained with 2% PTA. The scale bar is 100 nm. (C) Histogram depicting hydrodynamic size distribution of 4% PpIX-conjugated micelles by dynamic light scattering (DLS).