Fig. 3.

The discharge pattern in many pacemakers is characterized by a an autonomously augmenting ramp which generates action potentials that transition into a burst. Intrinsic properties (shaded blue) create the augmenting ramp during autonomous bursting in synaptic isolation. b Embedded in the network, this pattern is similarly present within the same neuron. In this condition, both synaptic input (yellow) and intrinsic properties (blue) will likely contribute to the generation of the ramp pattern. The integrated population activity (red) from the preBötC occurs in phase with the bursting of the individual neuron