Table 4.
The percentages of persons with Possible/Probable AD with a slow course from age of dementia onset to time points 1, 3, 5, and 7 years post onset are displayed. Slow course is defined as an average annual decline of no more than one point on MMSE (or average annual increase of no more than one point for CDR-sb and NPI total). The numbers and percentages of survivors represent those who survived up to each time point whereas those of the total represent the entire sample of 328 persons with AD.
| % of Survivors with Slow Course | % of Entire Sample (N = 328) with Slow Course | ||||||
|---|---|---|---|---|---|---|---|
| Onset to |
N Surviving |
Cognitive (MMSE) |
Functional (CDR-sb) |
NPS (NPI-total) |
Cognitive (MMSE) |
Functional (CDR-sb) |
NPS (NPI-total) |
| 1 Yr | 282 | 37.9 | 46.1 | 34.8 | 32.6 | 39.6 | 29.9 |
| 3 Yrs | 185 | 36.2 | 55.1 | 36.2 | 20.4 | 31.1 | 20.4 |
| 5 Yrs | 98 | 30.0 | 58.2 | 36.7 | 8.8 | 17.4 | 11.0 |
| 7 Yrs | 46 | 34.8 | 41.3 | 45.7 | 4.9 | 5.8 | 6.4 |
Note: a small number of subjects who scored 0 (floor) at their first observation were excluded from the analyses on the MMSE.