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Ability of MX-2401 to interact with model membranes. (A) Dose-dependent lipid flip-flop of C6-NBD-PC asymmetrically labeled POPC/POPG liposomes treated with MX-2401, daptomycin, and GMS in the presence of 5 mM CaCl2. (B) Dose-dependent calcein release from POPC/POPG liposomes treated with MX-2401, daptomycin, and GMS in the presence of 5 mM CaCl2. The error bars indicate standard deviations.
