Fig. 4.
Competitive titration of GST-PBP2a by ceftobiprole (A) and meropenem (B) in the presence of a fixed concentration (Kmapp = 1.6 μM) of BIO-AMP, including data points, error bars, best-fit lines, and best-fit parameter values. The data points obtained after 15 min of incubation are denoted by diamonds (♢), and those obtained after 30 min of incubation are denoted by boxes (□). Best-fit curves through data points obtained after 15 min of incubation are denoted by a solid line, and that obtained after 30 min of incubation is denoted by a dashed line. For all values, means ± the standard errors are given.