Table 4.

Distribution by influenza virus subtype and IC₅₀ of neuraminidase inhibitors at baseline

Virus subtype and parametera	Value for group
	Overall				300 mg				600 mg
	n	Peramivir	Oseltamivir	Zanamivir	n	Peramivir	Oseltamivir	Zanamivir	n	Peramivir	Oseltamivir	Zanamivir
A/H1	16b				7b				9b
Mean		21.79	87.11	1.42		22.02	83.52	1.44		21.62	89.91	1.41
SD		2.12	16.07	0.10		1.53	16.73	0.11		2.57	15.94	0.09
Min		16.19	57.42	1.26		19.20	57.42	1.26		16.19	58.28	1.27
Median		21.97	100.0	1.42		21.94	76.39	1.42		21.99	100.0	1.41
Max		25.02	100.0	1.62		24.13	100.0	1.62		25.02	100.0	1.56
A/H3	13				4				9
Mean		0.85	0.71	2.11		0.83	0.66	2.12		0.86	0.73	2.11
SD		0.10	0.11	0.16		0.10	0.11	0.08		0.10	0.11	0.19
Min		0.72	0.54	1.90		0.72	0.54	2.03		0.74	0.54	1.90
Median		0.83	0.70	2.07		0.82	0.64	2.13		0.83	0.73	2.07
Max		1.02	0.88	2.43		0.95	0.81	2.19		1.02	0.88	2.43
A/-	1				1				0
Mean		23.21	68.41	1.46		23.21	68.41	1.46
SD
Min		23.21	68.41	1.46		23.21	68.41	1.46
Median		23.21	68.41	1.46		23.21	68.41	1.46
Max		23.21	68.41	1.46		23.21	68.41	1.46
B	3				3				0
Mean		3.48	18.06	9.43		3.48	18.06	9.43
SD		0.06	2.53	0.30		0.06	2.53	0.30
Min		3.41	15.14	9.12		3.41	15.14	9.12
Median		3.49	19.33	9.46		3.49	19.33	9.46
Max		3.53	19.70	9.72		3.53	19.70	9.72
Unknown	1				0				1
Mean		3.75	14.76	9.48						3.75	14.76	9.48
SD
Min		3.75	14.76	9.48						3.75	14.76	9.48
Median		3.75	14.76	9.48						3.75	14.76	9.48
Max		3.75	14.76	9.48						3.75	14.76	9.48

^aMin, minimum; Max, maximum.

^bExcept for 4 failures in identification due to small sample volume, the H274Y mutation was identified in 12 patients (300-mg group, 5 patients; 600-mg group, 7 patients).