Table 3.
Annual percentages of resistant pneumococci in patients with pneumonia and AECOPD
| Antibiotic | No. (%) of resistant isolates from patients with pneumonia |
P value for trenda | No. (%) of resistant isolates from patients with AECOPD |
P value for trenda | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 2005 (n = 97) | 2006 (n = 104) | 2007 (n = 104) | 2008 (n = 96) | 2005 (n = 96) | 2006 (n = 103) | 2007 (n = 104) | 2008 (n = 95) | |||
| Oral benzylpenicillin | 18 (18.6) | 17 (16.3) | 9 (8.7) | 10 (10.4) | 0.036 | 21 (21.9) | 18 (17.5) | 19 (18.3) | 23 (24.2) | |
| Parenteral benzylpenicillin | 0 (0) | 0 | 0 (0) | 0 (0) | 0 (0) | 2 (1.9) | 0 (0) | 2 (2.1) | ||
| Amoxicillin | 2 (2.1) | 4 (3.8) | 2 (1.9) | 0 (0) | 2 (2.1) | 1 (1) | 4 (3.8) | 3 (3.2) | ||
| Cefotaxime | 1 (1) | 2 (1.9) | 1 (1) | 0 (0) | 0 (0) | 5 (4.9) | 1 (1) | 3 (3.2) | ||
| Erythromycin | 15 (15.5) | 12 (11.5) | 11 (10.6) | 12 (12.5) | 17 (17.7) | 24 (23.3) | 23 (22.1) | 15 (15.8) | ||
| Azithromycin | 15 (15.5) | 12 (11.5) | 11 (10.6) | 12 (12.5) | 17 (17.7) | 24 (23.3) | 23 (22.1) | 15 (15.8) | ||
| Quinupristin-dalfopristin | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 1 (1) | 0 (0) | 0 (0) | ||
| Clindamycin | 9 (9.3) | 7 (6.7) | 10 (9.6) | 7 (7.3) | 15 (15.6) | 20 (19.4) | 19 (18.3) | 9 (9.5) | ||
| Tetracycline | 15 (15.5) | 7 (6.7) | 7 (6.7) | 8 (8.3) | 19 (19.8) | 21 (20.4) | 20 (19.2) | 10 (10.5) | ||
| Trimethoprim-sulfamethoxazole | 20 (20.6) | 26 (25) | 12 (11.5) | 10 (10.4) | 0.028 | 19 (19.8) | 20 (19.4) | 21 (20.2) | 19 (20) | |
| Chloramphenicol | 2 (2.1) | 0 (0) | 1 (1) | 1 (1) | 5 (5.2) | 3 (2.9) | 2 (1.9) | 0 (0) | ||
| Rifampin | 1 (1) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | ||
| Ciprofloxacin | 10 (10.3) | 10 (9.6) | 4 (3.8) | 3 (3.1) | 0.015 | 14 (14.6) | 14 (13.6) | 4 (3.8) | 6 (6.3) | 0.009 |
| Levofloxacin | 0 (0) | 1 (1) | 1 (1) | 1 (1) | 6 (6.3) | 6 (5.8) | 1 (1) | 3 (3.2) | ||
a
Only statistically significant P values are shown.