Fig. 1.
Fatty acid biosynthesis in B. subtilis. Cerulenin, platensimycin, and platencin inhibit the 3-oxoacyl-ACP synthase FabF. Platencin targets FabF and FabHA/HB. Triclosan inhibits the enoyl-ACP-reductase FabI. Proteins belonging to the FapR regulon are circled. Proteins induced by fatty acid biosynthesis inhibitors are placed inside boxes. Modified according to Fujita et al. (9) with permission of the publisher.