Table 2.
Strain | Immunogen | Severity of EAG |
---|---|---|
SJL | Purified bovine α3(IV)NC1 | +++ |
C57/BL/6 | Purified bovine α3(IV)NC1 | + |
DBA/2 | Purified bovine α3(IV)NC1 | + |
CBA | Purified bovine α3(IV)NC1 | − |
A/J | Purified bovine α3(IV)NC1 | − |
AKR | Purified bovine α3(IV)NC1 | − |
DBA/1 | Recombinant human α3(IV)NC1 | +++ |
C57/BL/6 | Recombinant human α3(IV)NC1 | ++ |
AKR | Recombinant human α3(IV)NC1 | ++ |
NOD | Recombinant human α3(IV)NC1 | + |
C57/BL/6 | Recombinant mouse α3(IV)NC1 | +++ |
CD1 | Recombinant rat α3(IV)NC1 | +++ |
α3(IV)NC1, the non-collagenous domain of the alpha 3 chain of type IV collagen.