TABLE 1.
In vivo PAEs of free and total daptomycin concentrations of against S. aureus and S. pneumoniae
| Dose (mg/kg) | Total or free drug | PAE (h) against:
|
|
|---|---|---|---|
| S. aureus | S. pneumoniae | ||
| 2.5 | Total | 0.4 | 2.9 |
| Free | 5.5 | 8.8 | |
| 10 | Total | 5.0 | 6.6 |
| Free | 4.8 | 10.8 | |
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