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Effect of elevated intracellular cAMP on actin polymerization. (A) Treatment of cells with Fsk led to a significant decrease in cofilin phosphorylation at Ser3 (50%) compared with control (100%). The effect of Y-27632, although significant (15%; P < 0.05), was much less compared with that of Fsk. (B) Bar graph of results from three independent experiments similar to that in (A).
