Table 3.
Number of Control and EG Eyes Flagged as Changing, Based on the Difference between Baseline and Follow-up Exceeding the Repeatability Coefficient for that Parameter
| RNFLT | RNFLV | NCO Area | NCO Depth | BT Area | Rim Width | Rim Volume | PLTT | ALCS DepthNCO | ALCS DepthBM | |
|---|---|---|---|---|---|---|---|---|---|---|
| Control FU1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 2 |
| Estimated specificity (%) | 89 | 89 | 100 | 89 | 89 | 100 | 100 | 100 | 89 | 78 |
| 95% CI (%) | 56.5–98.0 | 56.5–98.0 | 70.1–100.0 | 56.5–98.0 | 56.5–98.0 | 70.1–100.0 | 70.1–100.0 | 70.1–100.0 | 56.5–98.0 | 45.3–93.7 |
| Control FU2 | 1 | 1 | 0 | 2 | 0 | 1 | 2 | 1 | 0 | 0 |
| Estimated specificity (%) | 89 | 89 | 100 | 78 | 100 | 89 | 78 | 89 | 100 | 100 |
| 95% CI (%) | 56.5–98.0 | 56.5–98.0 | 70.1–100.0 | 45.3–93.7 | 70.1–100.0 | 56.5–98.0 | 45.3–93.7 | 56.5–98 | 70.1–100.0 | 70.1–100.0 |
| EG FU1 | 0 | 0 | 0 | 2 | 0 | 5 | 5 | 0 | 6 | 6 |
| Positive hit rate (%) | 0 | 0 | 0 | 22 | 0 | 56 | 56 | 0 | 67 | 67 |
| 95% CI (%) | 0.0–29.9 | 0.0–29.9 | 0.0–29.9 | 6.3–54.7 | 0.0–29.9 | 26.7–81.1 | 26.7–81.1 | 0.0–29.9 | 35.4–87.9 | 35.4–87.9 |
| P | 0.1517 | 0.1517 | NA | 0.2635 | 0.1517 | 0.0043 | 0.0043 | NA | 0.0078 | 0.0289 |
| EG FU2 | 6 | 5 | 0 | 6 | 0 | 8 | 7 | 6 | 7 | 8 |
| Positive hit rate (%) | 67 | 56 | 0 | 67 | 0 | 89 | 78 | 67 | 78 | 89 |
| 95% CI (%) | 35.4–87.9 | 26.7–81.1 | 0.0–29.9 | 35.4–87.9 | 0.0–29.9 | 56.5–98.0 | 45.3–93.7 | 35.4–87.9 | 45.3–93.7 | 56.5–98.0 |
| P | 0.0078 | 0.0228 | NA | 0.0289 | NA | 0.0005 | 0.0092 | 0.0078 | 0.0004 | 0.0001 |
The 95% CI is listed under each proportion. The P values listed represent the result of a Z-test for two proportions comparing the positive hit rate for the treated eye group with that for the control eye group at each of the follow-up time points. Estimated specificity: (number of control eyes not changing/total control eyes) × 100; positive hit rate: (number of EG eyes changing/total EG eyes) × 100.