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IOP profile resulting from injection of 1 μL PBS boluses into a single mouse eye. The pressure jump arising from each injection can be seen, followed by a slow pressure decrease as fluid drains from the eye. Total compliance is calculated as the injected volume (1 μL), divided by the resulting pressure change (5–6 mm Hg). Note that the compliance measured in this manner includes the compliance of both the eye and of the perfusion system.
