Table 1.

Genes with Statistically Significant Changes in Gene Expression in 2D or 3D Differentiation Cultures Compared with ImM10 Cells in Growth Conditions Using Neurogenesis qRT-PCR Arrays

Gene	Accession No.	2D Fold Change	P	3D Fold Change	P
Apbb1	NM_009685	3.3	0.002	+	NS
Apoe	NM_009696	14.27	0.015	+	NS
Arnt2	NM_007488	+	NS	−2.25	0.05
Bai1	NM_174991	5.47	0.03	+	NS
Bdnf	NM_007540	+	NS	−2.32	0.049
Bmp15	NM_009757	++	—	ND	—
Bmp2	NM_007553	ND	—	++	—
Cdk5rap2	NM_145990	−1.66	0.003	+	NS
Cdk5rap3	NM_030248	1.56	0.002	+	NS
Cxcl1	NM_008176	−1.63	0.029	6.9	0.006
Dlg4	NM_007864	2.76	0.003	1.49	0.01
Dll1	NM_007865	+	NS	5.87	0.032
Egf	NM_010113	2.01	0.041	−3.63	0.006
Erbb2	NM_001003817	1.35	0.041	+	NS
Fez1	NM_183171	2.69	0.011	3.27	0.001
Fgf2	NM_008006	6.64	0.006	6.03	0.012
Flna	NM_010227	+	NS	−2.96	0.029
Gdnf	NM_010275	−8.84	0.009	+	NS
Gnao1	NM_010308	2.82	0.002	2.48	0.003
Grin1	NM_008169	3.58	0.035	+	NS
Hey1	NM_010423	+	NS	−8	0.015
Heyl	NM_013905	++	—	ND	—
Mdk	NM_010784	2.1	0.025	+	NS
Mef2c	NM_025282	ND	—	++	—
Notch2	NM_010928	2.41	0.023	3.55	0.022
Nptx1	NM_008730	13.2	0.019	165.4	0.028
Nrcam	NM_176930	++	—	++	—
Nrp1	NM_008737	2.39	0.004	2.14	0.004
Ntn1	NM_008744	+	NS	−7.36	0.03
Odz1	NM_011855	++	—	ND	—
Pard6b	NM_021409	1.49	0.024	+	NS
Pax6	NM_013627	2.88	0.009	+	NS
Ptn	NM_008973	+	NS	3.93	0.008
Sox3	NM_009237	++	—	ND	—

+, expressed; NS, no significant change vs. growth conditions; ++, expressed in differentiation conditions only, not growth, thus no fold change calculated; —, no P can be calculated for genes not expressed in ImM10 growth cultures; ND, not detected.