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Genetic animal model of diabetes. (A) Distribution of glucose in the offspring of a breeding pair TNFα+/+/Ins2Akita and TNFα−/−/Ins2Akita mice. The glucose was determined in the 4- to 5-week-old mice with a glucose monitor. The HI reading, which shows that the level of glucose is beyond the range of the meter, was designated 600 mg/dL. (B) The percentage of mice with blood glucose ≤250 mg/dL versus >250 mg/dL in the two lines is shown.
