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Tangent modulus (Etangent), the gradient of a tangent line drawn at a given point on the stress-strain curve, plotted as a function of applied stress for normal and RGE chicken corneas under the fourth cycle of posterior pressure loading. Error bars, SD. A 30–130% increase in Etangent, commonly considered a direct measure of tissue stiffness, is observed in RGE corneas compared with controls.
