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Active site of ODC bound to eflornithine. Select residues within 4Å of eflornithine-PLP are displayed. Eflornithine binds in the dimer interface; subunit A (green), subunit B (pink), eflornithine (magenta) and the cofactor pyridoxal 5’-phosphate (yellow). Nitrogen atoms are blue, oxygen red, sulfur yellow and phosphate orange. The figure was generated in PyMol [170] using the pdb coordinate file 2TOD.
