Table 4.
Activity of GSK-3 focused inhibitors on TbGSK3 and T. brucei
 | ||
|---|---|---|
| R1 | TbGSK3 IC50 (nM) |
T.brucei EC50 (nM) |
 |
4 | 50 |
 |
30 | 65 |
 |
46 | 200 |
 |
22 | 410 |
 |
30 | 460 |
 |
170 | 710 |
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