TABLE 2.

Characteristics and arrangement of the newly described ORFs from the clavulanic acid gene cluster^a

^aThe top panel represents the ORFs found in the inserts from pCEC001 and p667-3PB. B, BamHI; Ba, BalI; Bg, BglII; Bs, BstEII; Bx, BstXI; E, EcoRI; En, EcoNI; N, NaeI; Nc, NcoI; No, NotI; Nr, NruI; P, PstI; S, SphI. Only sites mentioned in the text are shown.

^bProtein with highest level of similarity to ORF-encoded protein.

^cIncludes stop codon.

^daa, amino acids.

^eProtein was annotated as a hypothetical protein, but conserved domains were detected, suggesting that the protein was an acetyltransferase (orf14) or carboxylase (orf17).