TABLE 2.

Effects of alterations in VS on the fungicidal effect of FLZ

Alterationa				Viability ratio (day 6/day 0)d
Minus lactic acid	Altered Na/Kc	Minus urea	Minus acetic acid	No FLZ	FLZe
				187	0.01
*b				181	0.04
	*			87	0.3
*	*			109	0.06
		*		150	0.02
*			*	833	168
			*	465	174

^aC. albicans ATCC 32354 was used in all media at 2 × 10⁴ cells/ml. All media were adjusted to an initial pH of 4.2.

^bAn asterisk indicates the item was removed or altered from the base VS medium in line 1.

^cThe Na and K concentrations were inverted to achieve levels found in normal serum (140 mM Na, 4 mM K).

^dThe viable cell ratio on day 6 was chosen as a convenient representation of the net effect.

^e64 μg/ml.