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Hemoglobin variants in S/β+ thalassemia and S/β° thalassemia
| Investigation | S/β+ thalassemia (Double Heterozygote) | S/β° thalassemia (Double Heterozygote) |
|---|---|---|
| HbS | Typically 60-80% | 75-90% |
| HbA1 | 15-30% | Absent unless transfused |
| HbA2 | 3-8% | 5-8% |
| HbF | 2-20%, higher for age in infants | 5-20% in adults, higher for age in infants |
