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. 2011 Mar 3;2(3):e125. doi: 10.1038/cddis.2011.8

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Copyright © 2011 Macmillan Publishers Limited

This work is licensed under the Creative Commons Attribution-NonCommercial-No Derivative Works 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/

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Caspase-10B is highly unstable, in contrast to other caspase-10 isoforms. (a) Whole cell extracts from SW480 and SH-EP cells overexpressing the indicated caspase-10 isoforms, untreated or treated with 20 ug/ml of CHX for various times, were analysed by immunoblotting for the presence of caspases-10, -8 and β-actin. (b) Whole cell extracts from SW480 and SH-EP-infected cells untreated or treated with 20 ug/ml of CHX, with or without lactacystin (10 μM for SH-EP or 50 μM for SW480) for 16 h, were analysed as in (a)

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