Fig. 3.

Box-plot of B2MG, OPN, and CFH concentrations according to HAT staging. ELISA results representing the measured concentrations (ng/ml) in S1 and S2 CSF samples of B2MG (n = 58), OPN (n = 57), and CFH (n = 52). Median and mean are represented as a solid line in the box and a diamond, respectively. Whisks are defined as 5th–95th percentile with outliers. Half-width of the notch was calculated automatically by the software. *** and * correspond to a significant difference between the two groups, respectively < 0.0001 and < 0.05 (Mann-Whitney U test). S1, stage 1 samples; S2, stage 2 samples.