Table 3.

Correlations Between Lipoprotein-Associated Phospholipase A₂ Mass and Activity and Other Important Cardiovascular Risk Factors

	Lp-PLA2
	Mass		Activity
Variable	DM	Non-DM	DM	Non-DM
Lp-PLA2 activity (nmol/min/mL)	0.35***	0.43***	1	1
Age (years)	0.14**	−0.001	0.05	0.13**
Total cholesterol (mg/dL)	0.19***	0.14**	0.38***	0.36***
LDL cholesterol (mg/dL)	0.21***	0.21***	0.54***	0.48***
HDL cholesterol (mg/dL)	0.06	−0.07	−0.26***	−0.36***
Triglycerides (mg/dL)	0.02	−0.04	0.19***	0.23***
APOB (mg/dL)	0.11*	0.13**	0.51***	0.48***
BMI (kg/m2)	−0.06	0.04	0.01	0.15**
Average waist (cm)	−0.05	0.03	0.04	0.17***
Visceral fat at L4–L5 (cm2)	−0.09*	0.03	0.07	0.17***
Subcutaneous fat at L4–L5 (cm2)	−0.05	0.03	0.07	0.12**
CRP (μg/mL)	−0.05	0.01	−0.15**	−0.08
HbA1c (%)	−0.07	−0.09*	0.02	−0.02
Insulin dose (units/kg/day) (DM)	−0.11*	NA	−0.02	NA
Duration of DM	0.15**	NA	0.01	NA

All correlations are controlled for gender.

^*P<0.05, **P<0.01, ***P<0.0001.

APOB, apolipoprotein B; BMI, body mass index; CRP, C-reactive protein; DM, diabetes mellitus; HbA1c, hemoglobin A1c; HDL, high-density lipoprotein; LDL, low-density lipoprotein; Lp-PLA₂, lipoprotein-associated phospholipase A₂; NA, not applicable.