Table 4.
Predictors of Progression of Coronary Calcification, a Priori Model in Multiple Logistic Regression Analysis (n = 1,021)
| Variable | OR (95% CI)* | P value |
|---|---|---|
| Baseline CVS | 2.15 (1.69–2.71) | <0.0001 |
| Diabetes | 2.89 (1.74–4.79) | <0.0001 |
| Age (10 years) | 2.19 (1.63–2.94) | <0.0001 |
| Sex (male) | 1.44 (0.88–2.36) | 0.15 |
| Hypertension | 1.62 (1.03–2.56) | 0.04 |
| Waist circumference | 1.76 (1.39–2.23) | <0.0001 |
| APOB | 0.77 (0.59–0.99) | 0.04 |
| Cystatin C | 1.23 (1.01–1.50) | 0.04 |
| Statin medication | 1.29 (0.73–2.31) | 0.37 |
| Smoker | ||
| Current | 1.12 (0.57–2.18) | 0.74 |
| Former | 1.09 (0.65–1.83) | 0.76 |
| Lp-PLA2 activity | 1.77 (1.08–2.91) | 0.02 |
*
Odds ratio (OR) and 95% confidence interval (CI) are per SD for each variable. The 1 SD value is as follows: calcium volume score (CVS), 4.6; waist circumference, 13.2 cm; apolipoprotein B (APOB), 25.9 mg/dL; cystatin C, 0.19 mg/L; lipoprotein-associated phospholipase A2 (Lp-PLA2), 4th quartile versus bottom three quartiles.