Table 5. HRs for all cancers associated with a two-point increment of the Mediterranean diet score for each category of tobacco smoking status.
| Cases | HRa (95% CI) | |
|---|---|---|
| All cancers | 30 731 | 0.96 (0.95–0.98) |
| Never smokers | 13 787 | 0.98 (0.96–1.00) |
| Former smokers | 8860 | 0.96 (0.93–0.98) |
| Current smokers | 7439 | 0.94 (0.91–0.97) |
| P for heterogeneity=0.07 | ||
| Cancers known to be related to smoking b , c | 8000 | 0.92 (0.89–0.94) |
| Never smokers | 2392 | 0.95 (0.90–0.99) |
| Former smokers | 2490 | 0.93 (0.89–0.98) |
| Current smokers | 3009 | 0.88 (0.84–0.92) |
| P for heterogeneity=0.04 | ||
| Cancers not known to be associated with smoking c , d | 11 218 | 0.98 (0.96–1.01) |
| Never smokers | 5645 | 0.97 (0.94–1.01) |
| Former smokers | 3205 | 0.99 (0.94–1.03) |
| Current smokers | 2104 | 0.99 (0.94–1.04) |
| P for heterogeneity=0.73 | ||
Abbreviations: CI=confidence interval; HR=hazard ratio.
Stratified by centre and sex, and adjusted for duration of smoking, smoking status, education, height, body mass index, total energy intake, physical activity, age at menarche, parity, menopausal status, oral contraceptive and hormone therapy use.
Smoking-associated cancers include cancers of the lung, kidney, upper aero-digestive tract, stomach, pancreas, bladder, liver and colorectal.
P for heterogeneity of smoking unrelated cancers vs smoking related cancers=0.0008
Smoking-unrelated cancers include cancers of the breast, prostate, and endometrium.