FIG. 1.

(A) In vitro growth rate of B. bovis in the presence of different concentrations of heparin 1 (in units per milliliter). Parasitic viability was monitored in subcultures for 10 days without heparin. +, viable parasites; −, dead parasites. (B) Percentage of abnormally multidividing forms of heparin-treated B. bovis parasites in cultures. *, significant difference (P < 0.01) between the heparin-treated groups and the control group. Each value represents the mean ± standard deviation for three separate trials, carried out in triplicate.