TABLE 2.
In vitro antimicrobial profiling of PX-6518a
| Category | Microorganism(s) |
|---|---|
| Viruses | Influenza virus, HIV |
| Bacteria | Escherichia coli, Salmonella paratyphi, Streptococcus pyogenes, Staphylococcus aureus, Pseudomonas aeruginosa, Mycobacterium smegmatis |
| Yeasts | Candida albicans, Cryptococcus neoformans |
| Fungi | Aspergillus niger, Microsporum canis, Trichophyton rubrum |
| Protozoa | Leishmania promastigotes, Plasmodium falciparum, Trypanosoma brucei, Trypanosoma cruzi, Toxoplasma gondii |
| Nematodes | Trichostrongylus colubriformis (larvae) |
a
IC50, >32 μg/ml.