Table 3.
Comparison of Mean Percent Adherence Between the Cellular Phone and Beeper Arms at Week 3 and Week 6a
| Adherence method | Baseline | Week 3 | p Value | Week 6 | p Value |
|---|---|---|---|---|---|
| MEMS | |||||
| Overall | 72.0 (59.3–84.8) | 73.9 (60.7–87.1) | |||
| CP | 85.3 (70.7–99.9) | 89.7 (76.5–102.9) | |||
| BP | 57.2 (41.8–72.7) | 56.3 (42.4–70.3) | |||
| Difference | 28.1 (6.8–49.4) | 0.0129 | 33.4 (14.1–52.6) | 0.002 | |
| (CP-BP) | |||||
| Pill Count | |||||
| Overall | 64.6 (51.8–77.5) | 69.1 (58.2–80.0) | 76.3 (66.4–86.1) | ||
| CP | 65.2 (46.9–83.5) | 76.5 (62.5–90.6) | 82.7 (68.7–96.8) | ||
| BP | 64.0 (44.7–83.3) | 60.8 (46.0–75.7) | 69.1 (54.2–83.9) | ||
| Difference | 1.2 (−25.4–27.8) | 15.7 (−4.7–36.1) | 0.1442 | 13.7 (−6.7–34.1) | 0.1529 |
| (CP-BP) | |||||
| Self-report | |||||
| Overall | 79.1 (68.8–89.3) | 85.3 (76.1–94.6) | 83.1 (70.4–95.7) | ||
| CP | 83.4 (69.1–97.7) | 91.1 (79.7–102.5) | 92.6 (77.5–107.7) | ||
| BP | 74.2 (59.2–89.2) | 78.9 (66.9–90.9) | 72.4 (56.5–88.3) | ||
| Difference | 9.2 (−11.5–29.9) | 12.2 (−4.3–28.8) | 0.1367 | 20.2 (−1.8–42.1) | 0.0689 |
| (CP-BP) | |||||
| CAS | |||||
| Overall | 69.7 (58.1–81.4) | 70.6 (58.6–82.5) | |||
| CP | 81.5 (67.8–95.1) | 83.4 (70.0–96.9) | |||
| BP | 56.7 (42.3–71.1) | 56.3 (42.2–70.4) | |||
| Difference | 24.8 (4.9–44.7) | 0.0176 | 27.1 (7.6–46.6) | 0.0094 | |
| (CP-BP) | |||||
MEMS, Midication Event Monitoring System; CP, cell phone; BP, beeper; CAS, composite adherence score.